Switch of ATP synthase
نویسندگان
چکیده
منابع مشابه
ATP synthase
All living species use ATP as a general source of energy by hydrolysing it into ADP and phosphate. In most species the regeneration of this vital molecule is catalysed by the H+-transporting F1F0 ATP synthases, marvellous machines that couple the flow of protons down an electrochemical gradient to form ATP from ADP and phosphate. Under certain circumstances these enzymes can also work in the re...
متن کاملQuick guide: ATP synthase
denotes the soluble catalytic headgroup where ATP synthesis and hydrolysis occur, and F o is the ion-translocating membrane domain (see Figure). What is it? An enzyme that uses energy from the transmembrane proton electrochemical gradient, generated by oxidative metabolism or photosynthesis, to produce ATP from ADP and P i. The enzyme can also act in reverse, hydrolysing ATP and pumping H + or ...
متن کاملATP-driven stepwise rotation of FoF1-ATP synthase.
FoF1-ATP synthase (FoF1) is a motor enzyme that couples ATP synthesis/hydrolysis with a transmembrane proton translocation. F1, a water-soluble ATPase portion of FoF1, rotates by repeating ATP-waiting dwell, 80 degrees substep rotation, catalytic dwell, and 40 degrees -substep rotation. Compared with F1, rotation of FoF1 has yet been poorly understood, and, here, we analyzed ATP-driven rotation...
متن کاملWinding and unwinding ATP synthase
ell migration depends on polarized actin polymerization at a cell's front edge. To get the most out of these actin networks, plasma membrane flexibility must be similarly polarized, according to results from Amit Vasanji, Paul Fox (Cleveland Clinic Foundation, Cleveland, OH), and colleagues. The group shows that the membrane is stiffest at the front of migrating endothelial cells. This oriented...
متن کاملImpaired ATP synthase assembly associated with a mutation in the human ATP synthase subunit 6 gene.
Mutations in human mitochondrial DNA are a well recognized cause of disease. A mutation at nucleotide position 8993 of human mitochondrial DNA, located within the gene for ATP synthase subunit 6, is associated with the neurological muscle weakness, ataxia, and retinitis pigmentosa (NARP) syndrome. To enable analysis of this mutation in control nuclear backgrounds, two different cell lines were ...
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ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 2001
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.41.s9_4